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  • Estimated Risks of Fatal Events Associated with Acetaminophen, Ibuprofen, and Naproxen Sodium Used for Analgesia

Estimated Risks of Fatal Events Associated with Acetaminophen, Ibuprofen, and Naproxen Sodium Used for Analgesia

June 25, 2015 Written by brendankiel

Kenneth J. Rothman* and Lee L. LanzaRTI Health Solutions, 3040 Cornwallis Road, P.O. Box 12194, Research Triangle Park, NC 27709-2194, USAAbstract

Objective: We assessed the net effect on risk of death for within-label use of acetaminophen and the two non- aspirin alternative oral non-prescription analgesics available in the U.S. (ibuprofen and naproxen sodium) in relation to upper gastrointestinal hemorrhage, liver failure, and renal failure.

Full PDF available here: Rothman-Lanza

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Media
National Pain Report
Prevalence and correlates of exceeding the labeled maximum dose of acetaminophen among adults in a U.S.-based internet survey
Webinar: Pediatric Pain Treatment and Telehealth: How New and Existing Telehealth Authorities Are Improving Pain Treatment for Kids


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Webinar: Responsible Pain Management
During the COVID-19 Pandemic


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PAPR Coalition members meet with Administration leadership at the White House on May 8, 2018.

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Incidence of Pain, as Compared to Major Conditions

Pain affects more Americans than diabetes, heart disease and cancer combined.

Condition Number of Sufferers
Chronic Pain 100 million Americans1
Diabetes 25.8 million Americans
(diagnosed and estimated undiagnosed)2
Coronary Heart Disease 16.3 million Americans3
Stroke 7.0 million Americans3
Cancer 11.9 million Americans4
Sources
1Institute of Medicine of The National Academies
2American Diabetes Association
3American Heart Association
4American Cancer Society

2018 PAPR Coalition