- Approximately 100 million Americans live with persistent pain – more than those affected by diabetes, heart disease and cancer combined
- Acetaminophen is used by over 50 million Americans each week
- More than 25 billion doses of acetaminophen are sold in the U.S. each year
- Acetaminophen is found in more than 500 different prescription and OTC medicines
- 120 million adults in the US have health condition for which acetaminophen may be the most appropriate pain reliever
- For example, approximately 37 million Americans have kidney disease, 740,000+ have kidney failure and 222,000+ live with a kidney transplant. (1)
- For kidney patients, acetaminophen is the preferred choice over non-steroidal anti-inflammatory drugs (NSAIDS) due to concerns about potential reduction in kidney function. (2)
- Pain is a significant public health problem that costs US society at least $560-$635 billion annually (equal to about $2,000.00 per person) (3)
- Comprehensive training in the development and execution of pain management plans for patients is frequently left out of graduate medical education curricula and current practice. (4)
- The number of cases of acetaminophen overdose has dropped over 20% since 2008 (5)
- Over 80% of 18-50 year-olds and 70% of 60+ year-olds use OTC pain relievers most often (6)
- In addition to evidence-based non-pharmacologic pain relief options (7), non-opioid analgesics, including over-the-counter analgesics, have been shown to be used successfully as part of multi-modal pain management. (8)
- 92% of older adults have chronic conditions and 41% have three or more chronic conditions
- The age 65+ population is projected to more than double from 40.3 million in 2010 to 83.7 million in 2050 (US Census Bureau, 2008).
1 Kidney Disease By The Numbers – American Society of Nephrology, March 2019 and United States Renal Data System. 2019 USRDS annual data report: Epidemiology of kidney disease in the United States. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2019.
2 Kidney Disease: A to Z Health Guide – National Kidney Foundation https://www.kidney.org/atoz/content/painMeds_Analgesics
3 Source: Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education, and Research – Institute of Medicine Report
4 Mezei L and BB Murinson. Pain education in North American medical schools. J Pain. December 2011. 12(12):1199-1208.
5 National Poison Data System. Feb 27, 2015 – Richard C. Dart, MD, PhD
6 Acetaminophen/OTC Pain Survey Outreach Report April 8, 2015 – Alliance for Aging Research
7 Tick H et al. Evidence-based nonpharmacologic strategies for comprehensive pain care the consortium pain task force white paper. March 2018. Explore: The Journal of Science and Healing.
8 Enthoven WT et al. Non-steroidal anti-inflammatory drugs for chronic low back pain. Cochrane Database Syst. Rev. February 2016. 10(2): CD012087.
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